Tuesday, February 6, 2018

DNA Project: Introduction


I’ve always had an interest in biology. When I was 11, I started collecting all sorts of info on conifers into a “book”. More recent projects include my ContentMine project, and an ongoing project on microscopic photography.

Plant cells Example photo (detail of the cross section of a basswood stem)

To my regret, however, I only recently got a decent introduction to the chemistry of DNA, and even then, there’s a lot left uncovered—obviously, it’s an introduction after all. It also raised a lot of questions, and gave me some new ideas, like: What if you were to thoroughly analyse an entire genome, figure out what does what, and then just… golfed it? The genome. What if you were to minify a genome? Those things were a bit out of scope of the class, however.

Luckily, there’s a thing called Profielwerkstuk in Dutch high school education. For your Profielwerkstuk you are ought to spend at least 80 hours on research into a topic of your choice. This includes setting up the project, reading literature, usually performing an experiment, writing the article, and, in the end, presenting your project.

Of course, I could spend that time on Citation.js, or on one of my other projects, but I’m probably going to spend that time on them anyway, and I want to learn something new. A perfect opportunity for me to answer some of those questions, and learn some more about DNA in the progress.

Later, I learnt about this paper, which is basically exactly the idea I mentioned above. Seeing the resources involved, it seems a bit out of the scope of my profielwerkstuk as well. However, there are plenty of other interesting things to figure out.

In the next few weeks, I will be reading literature to a) expand my basic knowledge on the subject past introduction-level and b) see what I could learn through experimentation, and which experiments I could perform in this project. My reading material includes:

I will also be putting out a series of blogposts, about inspirations, thoughts that came up while reading, ideas for the rest of the project, and more. Of course, I will also blog about the project itself.

In the meantime, if you are or know someone who can help me with actually performing those experiments (editing/sequencing DNA), please do contact me. General ideas, tips and feedback are of course also welcome.

This post is part of a series.

Sunday, February 4, 2018

Microscopic photography: Part 2

I promised more photos in the previous post, so here they are.



Penicillium with conidiophores
With conidiophores

Penicillium (conidiophore)
Detail of conidiophores

More fungi:
Fungus cells

Fungus cells

Cat brains:
Cat brain cells

This post is part of a series.